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WHO guidance on development of influenza vaccine reference viruses by reverse genetics

WHO guidance on
development of influenza
vaccine reference viruses
by reverse genetics

WHO/CDS/CSR/GIP/2005.6
Department of Communicable Disease
Surveillance and Response
Global Influenza Programme

WHO guidance on
development of influenza
vaccine reference viruses
by reverse genetics
World Health Organization
Department of Communicable Disease
Surveillance and Response
Global Influenza Programme

� World Health Organization 2005
All rights reserved.
The designations employed and the presentation of the material in this publication do not imply theexpression of any opinion whatsoever on the part of the World Health Organization concerning the legalstatus of any country, territory, city or area or of its authorities, or concerning the delimitation of itsfrontiers or boundaries. Dotted lines on maps represent approximate border lines for which there maynot yet be full agreement.
The mention of specific companies or of certain manufacturers products does not imply that they areendorsed or recommended by the World Health Organization in preference to others of a similar naturethat are not mentioned. Errors and omissions excepted, the names of proprietary products are distin-guished by initial capital letters
.
All reasonable precautions have been taken by the World Health Organization to verify the informationcontained in this publication. However, the published material is being distributed without warranty ofany kind, either express or implied. The responsibility for the interpretation and use of the material lieswith the reader. In no event shall the World Health Organization be liable for damages arising from itsuse.

WHO guidance on development of influenza vaccine reference viruses by reverse genetics

1

Contents

1. Introduction ...........................................

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